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Mitochondrial respiratory chain function promotes extracellular matrix integrity in cartilage
Energy metabolism and extracellular matrix (ECM) function together orchestrate and maintain tissue organization, but crosstalk between these processes is poorly understood. Here, we used single-cell RNA-Seq (scRNA-Seq) analysis to uncover the importance of the mitochondrial respiratory chain for ECM...
Autores principales: | Bubb, Kristina, Holzer, Tatjana, Nolte, Janica L., Krüger, Marcus, Wilson, Richard, Schlötzer-Schrehardt, Ursula, Brinckmann, Jürgen, Altmüller, Janine, Aszodi, Attila, Fleischhauer, Lutz, Clausen-Schaumann, Hauke, Probst, Kristina, Brachvogel, Bent |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8503590/ https://www.ncbi.nlm.nih.gov/pubmed/34560099 http://dx.doi.org/10.1016/j.jbc.2021.101224 |
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