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Mice lacking the proton channel Hv1 exhibit sex-specific differences in glucose homeostasis

Sex as a physiologic factor has a strong association with the features of metabolic syndrome. Our previous study showed that loss of the voltage-gated proton channel Hv1 inhibits insulin secretion and leads to hyperglycemia and glucose intolerance in male mice. However, there are significant differe...

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Detalles Bibliográficos
Autores principales: Pang, Huimin, Li, Jinzhi, Wang, Yuzhou, Su, Xiaomin, Gao, Yingtang, Li, Shu Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8503595/
https://www.ncbi.nlm.nih.gov/pubmed/34547291
http://dx.doi.org/10.1016/j.jbc.2021.101212