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Posttranslational modifications of serine protease TMPRSS13 regulate zymogen activation, proteolytic activity, and cell surface localization

TMPRSS13, a member of the type II transmembrane serine protease (TTSP) family, harbors four N-linked glycosylation sites in its extracellular domain. Two of the glycosylated residues are located in the scavenger receptor cysteine-rich (SRCR) protein domain, while the remaining two sites are in the c...

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Detalles Bibliográficos
Autores principales: Martin, Carly E., Murray, Andrew S., Sala-Hamrick, Kimberley E., Mackinder, Jacob R., Harrison, Evan C., Lundgren, Joseph G., Varela, Fausto A., List, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8503615/
https://www.ncbi.nlm.nih.gov/pubmed/34562451
http://dx.doi.org/10.1016/j.jbc.2021.101227