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Crystal structure of human cysteamine dioxygenase provides a structural rationale for its function as an oxygen sensor
Cysteamine dioxygenase (ADO) plays a vital role in regulating thiol metabolism and preserving oxygen homeostasis in humans by oxidizing the sulfur of cysteamine and N-terminal cysteine-containing proteins to their corresponding sulfinic acids using O(2) as a cosubstrate. However, as the only thiol d...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8503633/ https://www.ncbi.nlm.nih.gov/pubmed/34508780 http://dx.doi.org/10.1016/j.jbc.2021.101176 |