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A Cross-Reactive Monoclonal Antibody Against Neuraminidases of Both H9N2 and H3N2 Influenza Viruses Shows Protection in Mice Challenging Models

Neuraminidases (NAs) of H9N2 avian influenza virus (AIV) and H3N2 human seasonal influenza virus (HSIV) share similar antigenic structures. However, there are few reports on epitopes shared by these two NAs. We previously reported a monoclonal antibody (mAb) 1G8 against the NA of H9N2 AIV with neura...

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Detalles Bibliográficos
Autores principales: Wang, Fei, Wan, Zhimin, Wu, Jinsen, Wang, Yajuan, Fu, Hui, Shao, Hongxia, Qian, Kun, Gao, Wei, Ye, Jianqiang, Qin, Aijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8503672/
https://www.ncbi.nlm.nih.gov/pubmed/34646249
http://dx.doi.org/10.3389/fmicb.2021.730449