Cargando…

Cholesterol biosynthesis inhibitor RO 48-8071 inhibits pancreatic ductal adenocarcinoma cell viability by deactivating the JNK and ERK/MAPK signaling pathway

The morbidity and mortality of pancreatic cancer have been continuously increasing, causing seven deaths per 100,000 individuals/year. At present, effective therapies are severely lacking, thus, highlighting the importance of developing novel therapeutic approaches. The present study aimed to invest...

Descripción completa

Detalles Bibliográficos
Autores principales: Ding, Zhen, Gu, Yanan, Huang, Dake, Zhou, Hong, Zhu, Tingting, Luo, Xin, Zhang, Sumei, Zhang, Shengquan, Qian, Yeben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8503744/
https://www.ncbi.nlm.nih.gov/pubmed/34590153
http://dx.doi.org/10.3892/mmr.2021.12468