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Cholesterol biosynthesis inhibitor RO 48-8071 inhibits pancreatic ductal adenocarcinoma cell viability by deactivating the JNK and ERK/MAPK signaling pathway
The morbidity and mortality of pancreatic cancer have been continuously increasing, causing seven deaths per 100,000 individuals/year. At present, effective therapies are severely lacking, thus, highlighting the importance of developing novel therapeutic approaches. The present study aimed to invest...
Autores principales: | Ding, Zhen, Gu, Yanan, Huang, Dake, Zhou, Hong, Zhu, Tingting, Luo, Xin, Zhang, Sumei, Zhang, Shengquan, Qian, Yeben |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8503744/ https://www.ncbi.nlm.nih.gov/pubmed/34590153 http://dx.doi.org/10.3892/mmr.2021.12468 |
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