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G(2)/M cell cycle arrest and apoptosis induced by COH-203 in human promyelocytic leukemia HL-60 cells

The combretastatin A-4/oltipraz hybrid (COH), 5-(3-amino-4-methoxyphenyl)-4-(3,4,5-trimethoxyphenyl)-3H−1,2-dithiole-3-one (COH-203) is one of the COH compounds synthesized by our previous study, which has been reported to affect a number of cancer cell lines, such as SGC-7901, KB, HT-1080, HepG2, S...

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Detalles Bibliográficos
Autores principales: Lin, Jihong, Zhang, Lei, Wang, Zhiwei, Guan, Qi, Bao, Kai, Wu, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8503807/
https://www.ncbi.nlm.nih.gov/pubmed/34671429
http://dx.doi.org/10.3892/ol.2021.13076