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Molecular basis for ATPase-powered substrate translocation by the Lon AAA+ protease

The Lon AAA+ (adenosine triphosphatases associated with diverse cellular activities) protease (LonA) converts ATP-fuelled conformational changes into sufficient mechanical force to drive translocation of a substrate into a hexameric proteolytic chamber. To understand the structural basis for the sub...

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Detalles Bibliográficos
Autores principales: Li, Shanshan, Hsieh, Kan-Yen, Su, Shih-Chieh, Pintilie, Grigore D., Zhang, Kaiming, Chang, Chung-I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8503904/
https://www.ncbi.nlm.nih.gov/pubmed/34563541
http://dx.doi.org/10.1016/j.jbc.2021.101239