Inflammatory neuronal loss in the substantia nigra induced by systemic lipopolysaccharide is prevented by knockout of the P2Y(6) receptor in mice

Inflammation may contribute to multiple brain pathologies. One cause of inflammation is lipopolysaccharide/endotoxin (LPS), the levels of which are elevated in blood and/or brain during bacterial infections, gut dysfunction and neurodegenerative diseases, such as Parkinson’s disease. How inflammatio...

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Detalles Bibliográficos
Autores principales: Milde, Stefan, van Tartwijk, Francesca W., Vilalta, Anna, Hornik, Tamara C., Dundee, Jacob M., Puigdellívol, Mar, Brown, Guy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504061/
https://www.ncbi.nlm.nih.gov/pubmed/34635136
http://dx.doi.org/10.1186/s12974-021-02280-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504061/
https://www.ncbi.nlm.nih.gov/pubmed/34635136
http://dx.doi.org/10.1186/s12974-021-02280-2

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