Acetazolamide prevents hypoxia-induced reactive oxygen species generation and calcium release in pulmonary arterial smooth muscle

Upon sensing a reduction in local oxygen partial pressure, pulmonary vessels constrict, a phenomenon known as hypoxic pulmonary vasoconstriction. Excessive hypoxic pulmonary vasoconstriction can occur with ascent to high altitude and is a contributing factor to the development of high-altitude pulmo...

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Detalles Bibliográficos
Autores principales: Shimoda, Larissa A., Suresh, Karthik, Undem, Clark, Jiang, Haiyang, Yun, Xin, Sylvester, J.T., Swenson, Erik R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504243/
https://www.ncbi.nlm.nih.gov/pubmed/34646499
http://dx.doi.org/10.1177/20458940211049948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504243/
https://www.ncbi.nlm.nih.gov/pubmed/34646499
http://dx.doi.org/10.1177/20458940211049948

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