IRAK-4 in macrophages contributes to inflammatory osteolysis of wear particles around loosened hip implants

TLRs recognizing PAMPS play a role in local immunity and participate in implant-associated loosening. TLR-mediated signaling is primarily regulated by IL-1 receptor associated kinase-M (IRAK-M) negatively and IRAK-4 positively. Our previous studies have proved that wear particles promote endotoxin t...

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Detalles Bibliográficos
Autores principales: Zhang, Yang-chun, Xiao, Jian-hong, Deng, Shao-jie, Yi, Guo-liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504263/
https://www.ncbi.nlm.nih.gov/pubmed/34139893
http://dx.doi.org/10.1177/17534259211018740

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504263/
https://www.ncbi.nlm.nih.gov/pubmed/34139893
http://dx.doi.org/10.1177/17534259211018740

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