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IRAK-4 in macrophages contributes to inflammatory osteolysis of wear particles around loosened hip implants

TLRs recognizing PAMPS play a role in local immunity and participate in implant-associated loosening. TLR-mediated signaling is primarily regulated by IL-1 receptor associated kinase-M (IRAK-M) negatively and IRAK-4 positively. Our previous studies have proved that wear particles promote endotoxin t...

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Detalles Bibliográficos
Autores principales:	Zhang, Yang-chun, Xiao, Jian-hong, Deng, Shao-jie, Yi, Guo-liang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504263/ https://www.ncbi.nlm.nih.gov/pubmed/34139893 http://dx.doi.org/10.1177/17534259211018740

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