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Platelet‐derived growth factor (PDGF)‐BB protects dopaminergic neurons via activation of Akt/ERK/CREB pathways to upregulate tyrosine hydroxylase

AIMS: The neurotropic growth factor PDGF‐BB was shown to have vital neurorestorative functions in various animal models of Parkinson's disease (PD). Previous studies indicated that the regenerative property of PDGF‐BB contributes to the increased intensity of tyrosine hydroxylase (TH) fibers in...

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Detalles Bibliográficos
Autores principales: Chen, Huan, Teng, Yan, Chen, Xingmin, Liu, Zhihao, Geng, Fan, Liu, Yanzhuo, Jiang, Haisong, Wang, Ziyan, Yang, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504523/
https://www.ncbi.nlm.nih.gov/pubmed/34346167
http://dx.doi.org/10.1111/cns.13708