Cargando…

Platelet‐derived growth factor (PDGF)‐BB protects dopaminergic neurons via activation of Akt/ERK/CREB pathways to upregulate tyrosine hydroxylase

AIMS: The neurotropic growth factor PDGF‐BB was shown to have vital neurorestorative functions in various animal models of Parkinson's disease (PD). Previous studies indicated that the regenerative property of PDGF‐BB contributes to the increased intensity of tyrosine hydroxylase (TH) fibers in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Huan, Teng, Yan, Chen, Xingmin, Liu, Zhihao, Geng, Fan, Liu, Yanzhuo, Jiang, Haisong, Wang, Ziyan, Yang, Lu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504523/ https://www.ncbi.nlm.nih.gov/pubmed/34346167 http://dx.doi.org/10.1111/cns.13708

Ejemplares similares

Conditional deficiency of m6A methyltransferase Mettl14 in substantia nigra alters dopaminergic neuron function
por: Teng, Yan, et al.
Publicado: (2021)

Lateral Flow Aptasensor for Simultaneous Detection of Platelet-Derived Growth Factor-BB (PDGF-BB) and Thrombin
por: Liu, Guodong, et al.
Publicado: (2019)

PDGF-AA and PDGF-BB biosynthesis: proprotein processing in the Golgi complex and lysosomal degradation of PDGF-BB retained intracellularly
Publicado: (1992)

TRPC channel-mediated neuroprotection by PDGF involves Pyk2/ERK/CREB pathway
por: Yao, Honghong, et al.
Publicado: (2009)

Low plasma PDGF-BB levels are associated with estradiol in postmenopausal osteoporosis: PDGF-BB mediated by estradiol in women
por: Tang, Lanhua, et al.
Publicado: (2017)

A Promising Candidate in Tendon Healing Events—PDGF-BB
por: Chen, Yixuan, et al.
Publicado: (2022)

A fibronectin peptide redirects PDGF-BB/PDGFR complexes to macropinocytosis-like internalization and augments PDGF-BB survival signals
por: Zhu, Jia, et al.
Publicado: (2013)

Inhibition of PDGF-BB reduces alkali-induced corneal neovascularization in mice
por: Chen, Lei, et al.
Publicado: (2021)

A Tyrosine-Hydroxylase Characterization of Dopaminergic Neurons in the Honey Bee Brain
por: Tedjakumala, Stevanus R., et al.
Publicado: (2017)

Osteoclasts Control Osteoblast Chemotaxis via PDGF-BB/PDGF Receptor Beta Signaling
por: Sanchez-Fernandez, Maria Arantzazu, et al.
Publicado: (2008)

PDGF-BB modulates endothelial proliferation and angiogenesis in vitro via PDGF beta-receptors
Publicado: (1994)

The chemotactic response to PDGF-BB: evidence of a role for Ras
Publicado: (1995)

FoxO1 in dopaminergic neurons regulates energy homeostasis and targets tyrosine hydroxylase
por: Doan, Khanh V., et al.
Publicado: (2016)

Bone-derived PDGF-BB drives brain vascular calcification in male mice
por: Wang, Jiekang, et al.
Publicado: (2023)

Dopaminergic inhibition by G9a/Glp complex on tyrosine hydroxylase in nerve injury-induced hypersensitivity
por: Wang, Nan, et al.
Publicado: (2016)

Targeting retinal dopaminergic neurons in tyrosine hydroxylase-driven green fluorescent protein transgenic zebrafish
por: Meng, Shi, et al.
Publicado: (2008)

Striatal vessels receive phosphorylated tyrosine hydroxylase-rich innervation from midbrain dopaminergic neurons
por: Afonso-Oramas, Domingo, et al.
Publicado: (2014)

TLR4 signaling in VTA dopaminergic neurons regulates impulsivity through tyrosine hydroxylase modulation
por: Aurelian, L, et al.
Publicado: (2016)

PDGF-BB serum levels are decreased in adult onset Pompe patients
por: Fernández-Simón, Esther, et al.
Publicado: (2019)

PDGF-BB-derived supramolecular hydrogel for promoting skin wound healing
por: Jian, Ke, et al.
Publicado: (2022)

Noxa upregulation by oncogenic activation of MEK/ERK through CREB promotes autophagy in human melanoma cells
por: Liu, Yi Lun, et al.
Publicado: (2014)

Preoperative Serum Levels of PDGF-AB, PDGF-BB, TGF-α, EGF and ANG-2 in the Diagnosis of Endometrial Cancer
por: Kozłowski, Mateusz, et al.
Publicado: (2023)

Dopaminergic control of ADAMTS2 expression through cAMP/CREB and ERK: molecular effects of antipsychotics
por: Ruso-Julve, Fulgencio, et al.
Publicado: (2019)

Evaluation of Platelet-Rich Plasma by means of PRGF(®)-Endoret(®) protocol in leukemia cats: PDGF-BB and TGF-ß1 valuation
por: Miguel-Pastor, Laura, et al.
Publicado: (2023)

Decreased Platelet Counts and Serum Levels of VEGF-A, PDGF-BB, and BDNF in Extremely Preterm Infants Developing Severe ROP
por: Hellgren, Gunnel, et al.
Publicado: (2021)

PDGFR in PDGF-BB/PDGFR Signaling Pathway Does Orchestrates Osteogenesis in a Temporal Manner
por: Wang, Fangqian, et al.
Publicado: (2023)

A signal-enhanced and sensitive lateral flow aptasensor for the rapid detection of PDGF-BB
por: Cheng, Na, et al.
Publicado: (2020)

Regulation of T cell proliferation by JMJD6 and PDGF-BB during chronic hepatitis B infection
por: Chen, Cai-Feng, et al.
Publicado: (2014)

Lack or Inhibition of Dopaminergic Stimulation Induces a Development Increase of Striatal Tyrosine Hydroxylase-Positive Interneurons
por: Busceti, Carla Letizia, et al.
Publicado: (2012)

Goniolactone C, a Styryl Lactone Derivative, Inhibits PDGF-BB-Induced Vascular Smooth Muscle Cell Migration and Proliferation via PDGFR/ERK Signaling
por: Sun, Lan, et al.
Publicado: (2014)

Serial measurements of serum PDGF-AA, PDGF-BB, FGF2, and VEGF in multiresistant ovarian cancer patients treated with bevacizumab
por: Madsen, Christine Vestergaard, et al.
Publicado: (2012)

PDGF-BB Does Not Accelerate Healing in Diabetic Mice with Splinted Skin Wounds
por: Park, Shin Ae, et al.
Publicado: (2014)

Zoledronate suppressed angiogenesis and osteogenesis by inhibiting osteoclasts formation and secretion of PDGF-BB
por: Gao, Si-yong, et al.
Publicado: (2017)

Targeting the PDGF-B/PDGFR-β Interface with Destruxin A5 to Selectively Block PDGF-BB/PDGFR-ββ Signaling and Attenuate Liver Fibrosis
por: Wang, Xingqi, et al.
Publicado: (2016)

Evodiamine Attenuates PDGF-BB-Induced Migration of Rat Vascular Smooth Muscle Cells through Activating PPARγ
por: Ge, Xie, et al.
Publicado: (2015)

Effect on Osteogenic Differentiation of Genetically Modified IL4 or PDGF-BB Over-Expressing and IL4-PDGF-BB Co-Over-Expressing Bone Marrow-Derived Mesenchymal Stromal Cells In Vitro
por: Tsubosaka, Masanori, et al.
Publicado: (2021)

Transgenic Silkworm-Based Silk Gland Bioreactor for Large Scale Production of Bioactive Human Platelet-Derived Growth Factor (PDGF-BB) in Silk Cocoons
por: Chen, Wenjing, et al.
Publicado: (2018)

rhPDGF-BB Promotes Proliferation and Osteogenic Differentiation of Bone Marrow Stromal Cells from Streptozotocin-Induced Diabetic Rats through ERK Pathway
por: Zhao, Yanfang, et al.
Publicado: (2014)

Role of hyperbaric oxygen therapy in PDGF-BB-mediated astrogliosis in traumatic brain injury rats associated with ERK1/2 signaling pathway inhibition
por: Xiu, Guanghui, et al.
Publicado: (2023)

Dopaminergic Receptors and Tyrosine Hydroxylase Expression in Peripheral Blood Mononuclear Cells: A Distinct Pattern in Central Obesity
por: Leite, Fernanda, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_p9mpt7shsolpad5akmtb8uj7vu