Cargando…
Platelet‐derived growth factor (PDGF)‐BB protects dopaminergic neurons via activation of Akt/ERK/CREB pathways to upregulate tyrosine hydroxylase
AIMS: The neurotropic growth factor PDGF‐BB was shown to have vital neurorestorative functions in various animal models of Parkinson's disease (PD). Previous studies indicated that the regenerative property of PDGF‐BB contributes to the increased intensity of tyrosine hydroxylase (TH) fibers in...
Autores principales: | Chen, Huan, Teng, Yan, Chen, Xingmin, Liu, Zhihao, Geng, Fan, Liu, Yanzhuo, Jiang, Haisong, Wang, Ziyan, Yang, Lu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504523/ https://www.ncbi.nlm.nih.gov/pubmed/34346167 http://dx.doi.org/10.1111/cns.13708 |
Ejemplares similares
-
Conditional deficiency of m6A methyltransferase Mettl14 in substantia nigra alters dopaminergic neuron function
por: Teng, Yan, et al.
Publicado: (2021) -
Lateral Flow Aptasensor for Simultaneous Detection of Platelet-Derived Growth Factor-BB (PDGF-BB) and Thrombin
por: Liu, Guodong, et al.
Publicado: (2019) -
PDGF-AA and PDGF-BB biosynthesis: proprotein processing in the Golgi complex and lysosomal degradation of PDGF-BB retained intracellularly
Publicado: (1992) -
TRPC channel-mediated neuroprotection by PDGF involves Pyk2/ERK/CREB pathway
por: Yao, Honghong, et al.
Publicado: (2009) -
Low plasma PDGF-BB levels are associated with estradiol in postmenopausal osteoporosis: PDGF-BB mediated by estradiol in women
por: Tang, Lanhua, et al.
Publicado: (2017)