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Evaluation of a Clinically Relevant Drug–Drug Interaction Between Rosuvastatin and Clopidogrel and the Risk of Hepatotoxicity

Purpose: The combination therapy of rosuvastatin (RSV) and the platelet inhibitor clopidogrel (CP) is widely accepted in the management of cardiovascular diseases. The objective of the present study was to identify the mechanism of RSV–CP DDI and evaluate the risk of hepatotoxicity associated with t...

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Detalles Bibliográficos
Autores principales: Ning, Chen, Su, Shengdi, Li, Jiaming, Kong, Dexuan, Cai, Hui, Qin, Zhiying, Xing, Han, Chen, Xijing, He, Jiake
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504577/
https://www.ncbi.nlm.nih.gov/pubmed/34646133
http://dx.doi.org/10.3389/fphar.2021.715577