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Evaluation of a Clinically Relevant Drug–Drug Interaction Between Rosuvastatin and Clopidogrel and the Risk of Hepatotoxicity
Purpose: The combination therapy of rosuvastatin (RSV) and the platelet inhibitor clopidogrel (CP) is widely accepted in the management of cardiovascular diseases. The objective of the present study was to identify the mechanism of RSV–CP DDI and evaluate the risk of hepatotoxicity associated with t...
Autores principales: | Ning, Chen, Su, Shengdi, Li, Jiaming, Kong, Dexuan, Cai, Hui, Qin, Zhiying, Xing, Han, Chen, Xijing, He, Jiake |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504577/ https://www.ncbi.nlm.nih.gov/pubmed/34646133 http://dx.doi.org/10.3389/fphar.2021.715577 |
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