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ORFLine: a bioinformatic pipeline to prioritize small open reading frames identifies candidate secreted small proteins from lymphocytes

MOTIVATION: The annotation of small open reading frames (smORFs) of <100 codons (<300 nucleotides) is challenging due to the large number of such sequences in the genome. RESULTS: In this study, we developed a computational pipeline, which we have named ORFLine, that stringently identifies smO...

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Detalles Bibliográficos
Autores principales: Hu, Fengyuan, Lu, Jia, Matheson, Louise S, Díaz-Muñoz, Manuel D, Saveliev, Alexander, Xu, Jinbo, Turner, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504629/
https://www.ncbi.nlm.nih.gov/pubmed/33970232
http://dx.doi.org/10.1093/bioinformatics/btab339