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Identification of cell-type-specific marker genes from co-expression patterns in tissue samples

MOTIVATION: Marker genes, defined as genes that are expressed primarily in a single-cell type, can be identified from the single-cell transcriptome; however, such data are not always available for the many uses of marker genes, such as deconvolution of bulk tissue. Marker genes for a cell type, howe...

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Detalles Bibliográficos
Autores principales: Qiu, Yixuan, Wang, Jiebiao, Lei, Jing, Roeder, Kathryn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504631/
https://www.ncbi.nlm.nih.gov/pubmed/33904573
http://dx.doi.org/10.1093/bioinformatics/btab257