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Differential gene expression analysis for multi-subject single-cell RNA-sequencing studies with aggregateBioVar

MOTIVATION: Single-cell RNA-sequencing (scRNA-seq) provides more granular biological information than bulk RNA-sequencing; bulk RNA sequencing remains popular due to lower costs which allows processing more biological replicates and design more powerful studies. As scRNA-seq costs have decreased, co...

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Detalles Bibliográficos
Autores principales: Thurman, Andrew L, Ratcliff, Jason A, Chimenti, Michael S, Pezzulo, Alejandro A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504643/
https://www.ncbi.nlm.nih.gov/pubmed/33970215
http://dx.doi.org/10.1093/bioinformatics/btab337