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Neuroinductive properties of mGDNF depend on the producer, E. Coli or human cells

The glial cell line‐derived neurotrophic factor (GDNF) is involved in the survival of dopaminergic neurons. Besides, GDNF can also induce axonal growth and creation of new functional synapses. GDNF potential is promising for translation to treat diseases associated with neuronal death: neurodegenera...

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Detalles Bibliográficos
Autores principales: Shamadykova, Dzhirgala V., Panteleev, Dmitry Y., Kust, Nadezhda N., Savchenko, Ekaterina A., Rybalkina, Ekaterina Y., Revishchin, Alexander V., Pavlova, Galina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504721/
https://www.ncbi.nlm.nih.gov/pubmed/34634077
http://dx.doi.org/10.1371/journal.pone.0258289