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A more accurate method for colocalisation analysis allowing for multiple causal variants

In genome-wide association studies (GWAS) it is now common to search for, and find, multiple causal variants located in close proximity. It has also become standard to ask whether different traits share the same causal variants, but one of the popular methods to answer this question, coloc, makes th...

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Detalles Bibliográficos
Autor principal: Wallace, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504726/
https://www.ncbi.nlm.nih.gov/pubmed/34587156
http://dx.doi.org/10.1371/journal.pgen.1009440