Tissue pharmacokinetics of DHP107, a novel lipid‐based oral formulation of paclitaxel, in mice and patients by positron emission tomography

DHP107 is a newly developed lipid‐based oral formulation of paclitaxel. We evaluated the in vivo tissue pharmacokinetics (PKs) of DHP107 in mice and patients using positron emission tomography (PET). Radioisotope‐labeled [(3)H]DHP107 and [(18)F]DHP107 for oral administration were formulated in the s...

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Detalles Bibliográficos
Autores principales: Moon, Byung Seok, Park, Hyun Soo, Sunwoo, Jung, Lee, In‐Hyun, Kim, Anhye, Moon, Seol Ju, Lee, Heechan, Son, Min Hee, Kim, Su Bin, Park, Sun Mi, Woo, Sang‐Keun, Jang, Jun‐Hee, Kim, Bom Sahn, Kim, Jee Hyun, Kim, Sang Eun, Lee, Howard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504807/
https://www.ncbi.nlm.nih.gov/pubmed/34085761
http://dx.doi.org/10.1111/cts.13003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504807/
https://www.ncbi.nlm.nih.gov/pubmed/34085761
http://dx.doi.org/10.1111/cts.13003

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