Effects of vancomycin‐induced gut microbiome alteration on the pharmacodynamics of metformin in healthy male subjects

Metformin is a major treatment for type 2 diabetes. This study was conducted to investigate the impact of gut microbiome dysbiosis on the pharmacokinetics and antihyperglycemic effects of metformin. Healthy adult males aged 19–45 years with no defecation abnormalities were recruited for this 4‐perio...

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Detalles Bibliográficos
Autores principales: Kim, Eunwoo, Kim, Andrew Hyoungjin, Lee, Yujin, Ji, Sang Chun, Cho, Joo‐Youn, Yu, Kyung‐Sang, Chung, Jae‐Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504811/
https://www.ncbi.nlm.nih.gov/pubmed/33982376
http://dx.doi.org/10.1111/cts.13051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504811/
https://www.ncbi.nlm.nih.gov/pubmed/33982376
http://dx.doi.org/10.1111/cts.13051

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