Safety and pharmacokinetics of docetaxel in combination with pegvorhyaluronidase alfa in patients with non‐small cell lung cancer

This open‐label, phase Ib study (NCT02346370) assessed the effect of pegvorhyaluronidase alfa (PVHA; PEGPH20) on the plasma pharmacokinetics (PKs) and safety of docetaxel in 15 patients with stage IIIB/IV non‐small cell lung cancer (NSCLC). The docetaxel PK profile from this study was consistent wit...

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Detalles Bibliográficos
Autores principales: Heineman, Thomas, Baumgart, Megan, Nanavati, Charvi, Gabrail, Nash, Van Wart, Scott A., Mager, Donald E., Maneval, Daniel C., Fathallah, Anas M., Sekulovich, Rose E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504814/
https://www.ncbi.nlm.nih.gov/pubmed/33982408
http://dx.doi.org/10.1111/cts.13041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504814/
https://www.ncbi.nlm.nih.gov/pubmed/33982408
http://dx.doi.org/10.1111/cts.13041

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