Safety, tolerability, and pharmacokinetics of single‐ and multiple‐dose administration of islatravir (MK‐8591) in adults without HIV

Islatravir (MK‐8591) is a nucleoside analogue in development for the treatment and prevention of HIV‐1. Two phase 1 trials were conducted during initial evaluation of islatravir: rising single doses (Study 1) and rising multiple doses (Study 2) of oral islatravir in male and female participants with...

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Detalles Bibliográficos
Autores principales: Matthews, Randolph P., Ankrom, Wendy, Friedman, Evan, Jackson Rudd, Deanne, Liu, Yang, Mogg, Robin, Panebianco, Deborah, De Lepeleire, Inge, Petkova, Magdalena, Grobler, Jay A., Stoch, Selwyn Aubrey, Iwamoto, Marian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504818/
https://www.ncbi.nlm.nih.gov/pubmed/34463432
http://dx.doi.org/10.1111/cts.13048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504818/
https://www.ncbi.nlm.nih.gov/pubmed/34463432
http://dx.doi.org/10.1111/cts.13048

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