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Application of machine learning to predict reduction in total PANSS score and enrich enrollment in schizophrenia clinical trials

Clinical trial efficiency, defined as facilitating patient enrollment, and reducing the time to reach safety and efficacy decision points, is a critical driving factor for making improvements in therapeutic development. The present work evaluated a machine learning (ML) approach to improve phase II...

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Detalles Bibliográficos
Autores principales: Podichetty, Jagdeep T., Silvola, Rebecca M., Rodriguez‐Romero, Violeta, Bergstrom, Richard F., Vakilynejad, Majid, Bies, Robert R., Stratford, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504834/
https://www.ncbi.nlm.nih.gov/pubmed/33939284
http://dx.doi.org/10.1111/cts.13035