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SIRT7 regulates lipogenesis in adipocytes through deacetylation of PPARγ2

AIMS/INTRODUCTION: Peroxisome proliferator‐activated receptor (PPAR)‐γ2 is a transcription factor crucial for regulating adipogenesis and glucose/lipid metabolism, and synthetic PPARγ ligands, such as thiazolidinediones, are effective oral medication for type 2 diabetes. Sirtuin 7 (SIRT7), a nicotin...

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Detalles Bibliográficos
Autores principales: Akter, Fatema, Tsuyama, Tomonori, Yoshizawa, Tatsuya, Sobuz, Shihab U., Yamagata, Kazuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504911/
https://www.ncbi.nlm.nih.gov/pubmed/33955199
http://dx.doi.org/10.1111/jdi.13567