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microRNA-mediated regulation of microRNA machinery controls cell fate decisions

microRNAs associate with Argonaute proteins, forming the microRNA-induced silencing complex (miRISC), to repress target gene expression post-transcriptionally. Although microRNAs are critical regulators in mammalian cell differentiation, our understanding of how microRNA machinery, such as the miRIS...

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Detalles Bibliográficos
Autores principales: Liu, Qiuying, Novak, Mariah K, Pepin, Rachel M, Eich, Taylor, Hu, Wenqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504967/
https://www.ncbi.nlm.nih.gov/pubmed/34596044
http://dx.doi.org/10.7554/eLife.72289