Cell-to-cell transmission of HSV1 in human keratinocytes in the absence of the major entry receptor, nectin1

Herpes simplex virus 1 (HSV1) infects the stratified epithelia of the epidermis, oral or genital mucosa, where the main cell type is the keratinocyte. Here we have used nTERT human keratinocytes to generate a CRISPR-Cas9 knockout (KO) of the primary candidate HSV1 receptor, nectin1, resulting in a c...

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Detalles Bibliográficos
Autores principales: Kite, Joanne, Russell, Tiffany, Jones, Juliet, Elliott, Gillian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505007/
https://www.ncbi.nlm.nih.gov/pubmed/34587223
http://dx.doi.org/10.1371/journal.ppat.1009631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505007/
https://www.ncbi.nlm.nih.gov/pubmed/34587223
http://dx.doi.org/10.1371/journal.ppat.1009631

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