Nicotine Exacerbates TAAD Formation Induced by Smooth Muscle-Specific Deletion of the TGF-β Receptor 2

Tobacco smoke is an established risk factor for thoracic aortic aneurysms and dissections (TAAD). However, little is known about its underlying mechanisms due to the lack of validated animal models. The present study developed a mouse model that may be utilized to investigate exacerbation of TAAD fo...

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Detalles Bibliográficos
Autores principales: Chun, Changzoon, Qi, Xiaoyan, Wang, Fen, Madrid, Kyle B., Saldarriaga, Lennon A., Fisch, Max R., Brantly, Mark L., Upchurch, Gilbert R., Jiang, Zhihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505064/
https://www.ncbi.nlm.nih.gov/pubmed/34646889
http://dx.doi.org/10.1155/2021/6880036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505064/
https://www.ncbi.nlm.nih.gov/pubmed/34646889
http://dx.doi.org/10.1155/2021/6880036

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