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Notch1 Signaling Contributes to Mechanical Allodynia Associated with Cyclophosphamide-Induced Cystitis by Promoting Microglia Activation and Neuroinflammation

AIMS: Notch1 signaling regulates microglia activation, which promotes neuroinflammation. Neuroinflammation plays an essential role in various kinds of pain sensation, including bladder-related pain in bladder pain syndrome/interstitial cystitis (BPS/IC). However, the impact of Notch1 signaling on me...

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Detalles Bibliográficos
Autores principales: Chen, Jialiang, Ding, Honglu, Liu, Bolong, Zhou, Xiangfu, Zhou, Xin, Lin, Zhijun, Yang, Fei, Zhan, Hailun, Xiao, Hengjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505104/
https://www.ncbi.nlm.nih.gov/pubmed/34646085
http://dx.doi.org/10.1155/2021/1791222