Cargando…

Low-dose metronomic doxorubicin inhibits mobilization and differentiation of endothelial progenitor cells through REDD1-mediated VEGFR-2 downregulation

Low-dose metronomic chemotherapy has been introduced as a less toxic and effective strategy to inhibit tumor angiogenesis, but its anti-angiogenic mechanism on endothelial progenitor cells (EPCs) has not been fully elucidated. Here, we investigated the functional role of regulated in development and...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Minsik, Kim, Ji Yoon, Kim, Joohwan, Lee, Jeong-Hyung, Kwon, Young-Guen, Kim, Young-Myeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505230/
https://www.ncbi.nlm.nih.gov/pubmed/34488932
http://dx.doi.org/10.5483/BMBRep.2021.54.9.096