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P11 deficiency increases stress reactivity along with HPA axis and autonomic hyperresponsiveness

Patients suffering from mood disorders and anxiety commonly exhibit hypothalamic–pituitary–adrenocortical (HPA) axis and autonomic hyperresponsiveness. A wealth of data using preclinical animal models and human patient samples indicate that p11 deficiency is implicated in depression-like phenotypes....

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Detalles Bibliográficos
Autores principales: Sousa, Vasco C., Mantas, Ioannis, Stroth, Nikolas, Hager, Torben, Pereira, Marcela, Jiang, Haitang, Jabre, Sandra, Paslawski, Wojciech, Stiedl, Oliver, Svenningsson, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505237/
https://www.ncbi.nlm.nih.gov/pubmed/33005029
http://dx.doi.org/10.1038/s41380-020-00887-0