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Activation of the p11/SMARCA3/Neurensin-2 pathway in parvalbumin interneurons mediates the response to chronic antidepressants

The delayed behavioral response to chronic antidepressants depends on dynamic changes in the hippocampus. It was suggested that the antidepressant protein p11 and the chromatin remodeling factor SMARCA3 mediate this delayed response by inducing transcriptional changes in hippocampal neurons. However...

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Detalles Bibliográficos
Autores principales: Umschweif, Gali, Medrihan, Lucian, McCabe, Kathryn A., Sagi, Yotam, Greengard, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505248/
https://www.ncbi.nlm.nih.gov/pubmed/33723417
http://dx.doi.org/10.1038/s41380-021-01059-4