Human cerebral organoids establish subcortical projections in the mouse brain after transplantation

Numerous studies have used human pluripotent stem cell-derived cerebral organoids to elucidate the mystery of human brain development and model neurological diseases in vitro, but the potential for grafted organoid-based therapy in vivo remains unknown. Here, we optimized a culturing protocol capabl...

Descripción completa

Detalles Bibliográficos
Autores principales: Dong, Xin, Xu, Shi-Bo, Chen, Xin, Tao, Mengdan, Tang, Xiao-Yan, Fang, Kai-Heng, Xu, Min, Pan, Yufeng, Chen, Yuejun, He, Shuijin, Liu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505255/
https://www.ncbi.nlm.nih.gov/pubmed/33051604
http://dx.doi.org/10.1038/s41380-020-00910-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505255/
https://www.ncbi.nlm.nih.gov/pubmed/33051604
http://dx.doi.org/10.1038/s41380-020-00910-4

Ejemplares similares