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Human cerebral organoids establish subcortical projections in the mouse brain after transplantation
Numerous studies have used human pluripotent stem cell-derived cerebral organoids to elucidate the mystery of human brain development and model neurological diseases in vitro, but the potential for grafted organoid-based therapy in vivo remains unknown. Here, we optimized a culturing protocol capabl...
Autores principales: | Dong, Xin, Xu, Shi-Bo, Chen, Xin, Tao, Mengdan, Tang, Xiao-Yan, Fang, Kai-Heng, Xu, Min, Pan, Yufeng, Chen, Yuejun, He, Shuijin, Liu, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505255/ https://www.ncbi.nlm.nih.gov/pubmed/33051604 http://dx.doi.org/10.1038/s41380-020-00910-4 |
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