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Tumour draining lymph node-generated CD8 T cells play a role in controlling lung metastases after a primary tumour is removed but not when adjuvant immunotherapy is used

Surgical resection of cancer remains the frontline therapy for millions of patients annually, but post-operative recurrence is common, with a relapse rate of around 45% for non-small cell lung cancer. The tumour draining lymph nodes (dLN) are resected at the time of surgery for staging purposes, and...

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Detalles Bibliográficos
Autores principales: Fear, Vanessa S., Forbes, Catherine A., Neeve, Samuel A., Fisher, Scott A., Chee, Jonathan, Waithman, Jason, Ma, Shao Kang, Lake, Richard, Nowak, Anna K., Creaney, Jenette, Brown, Matthew D., Saunders, Christobel, Robinson, Bruce W. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505306/
https://www.ncbi.nlm.nih.gov/pubmed/33835222
http://dx.doi.org/10.1007/s00262-021-02934-3