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CMTM6 expression in M2 macrophages is a potential predictor of PD-1/PD-L1 inhibitor response in colorectal cancer

BACKGROUND: CMTM6 is a novel key regulator of PD-L1. High expression of both CMTM6 and PD-L1 may predict the benefit of PD-1 axis blockade in lung cancer. We aimed to investigate the expression pattern of CMTM6 between mismatch repair-defective (dMMR) and mismatch repair-proficient (pMMR) colorectal...

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Detalles Bibliográficos
Autores principales: Wu, Xuehui, Lan, Xiaoliang, Hu, Wanming, Zhang, Wanning, Lai, Xiangmeng, Xu, Shaowan, Li, Jiaoying, Qiu, Weihao, Wang, Wei, Xiao, Jianbiao, Wang, Feifei, Ding, Yanqing, Liang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505364/
https://www.ncbi.nlm.nih.gov/pubmed/33818637
http://dx.doi.org/10.1007/s00262-021-02931-6