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Current Ceftriaxone Dose Recommendations are Adequate for Most Critically Ill Children: Results of a Population Pharmacokinetic Modeling and Simulation Study

BACKGROUND AND OBJECTIVE: Ceftriaxone is a cornerstone antibiotic for critically ill children with severe infections. Despite its widespread use, information on the pharmacokinetics of ceftriaxone is lacking in this population. We aimed to determine ceftriaxone pharmacokinetics in critically ill chi...

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Detalles Bibliográficos
Autores principales: Hartman, Stan J. F., Upadhyay, Parth J., Hagedoorn, Nienke N., Mathôt, Ron A. A., Moll, Henriëtte A., van der Flier, Michiel, Schreuder, Michiel F., Brüggemann, Roger J., Knibbe, Catherijne A., de Wildt, Saskia N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505376/
https://www.ncbi.nlm.nih.gov/pubmed/34036552
http://dx.doi.org/10.1007/s40262-021-01035-9