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Immune pathways and TP53 missense mutations are associated with longer survival in canine osteosarcoma

Osteosarcoma affects about 2.8% of dogs with cancer, with a one-year survival rate of approximately 45%. The purpose of this study was to characterize mutation and expression profiles of osteosarcoma and its association with outcome in dogs. The number of somatic variants identified across 26 sample...

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Detalles Bibliográficos
Autores principales: Das, Sunetra, Idate, Rupa, Regan, Daniel P., Fowles, Jared S., Lana, Susan E., Thamm, Douglas H., Gustafson, Daniel L., Duval, Dawn L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505454/
https://www.ncbi.nlm.nih.gov/pubmed/34635775
http://dx.doi.org/10.1038/s42003-021-02683-0