Enduring glucocorticoid-evoked exacerbation of synaptic plasticity disruption in male rats modelling early Alzheimer’s disease amyloidosis

Synaptic dysfunction is a likely proximate cause of subtle cognitive impairment in early Alzheimer’s disease. Soluble oligomers are the most synaptotoxic forms of amyloid ß-protein (Aß) and mediate synaptic plasticity disruption in Alzheimer’s disease amyloidosis. Because the presence and extent of...

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Detalles Bibliográficos
Autores principales: Qi, Yingjie, Klyubin, Igor, Ondrejcak, Tomas, Hu, Neng-Wei, Rowan, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505492/
https://www.ncbi.nlm.nih.gov/pubmed/34188184
http://dx.doi.org/10.1038/s41386-021-01056-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505492/
https://www.ncbi.nlm.nih.gov/pubmed/34188184
http://dx.doi.org/10.1038/s41386-021-01056-9

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