Structural mechanism of GTPase-powered ribosome-tRNA movement

GTPases are regulators of cell signaling acting as molecular switches. The translational GTPase EF-G stands out, as it uses GTP hydrolysis to generate force and promote the movement of the ribosome along the mRNA. The key unresolved question is how GTP hydrolysis drives molecular movement. Here, we...

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Detalles Bibliográficos
Autores principales: Petrychenko, Valentyn, Peng, Bee-Zen, de A. P. Schwarzer, Ana C., Peske, Frank, Rodnina, Marina V., Fischer, Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505512/
https://www.ncbi.nlm.nih.gov/pubmed/34635670
http://dx.doi.org/10.1038/s41467-021-26133-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505512/
https://www.ncbi.nlm.nih.gov/pubmed/34635670
http://dx.doi.org/10.1038/s41467-021-26133-x

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