Selective STAT3 Inhibitor Alantolactone Ameliorates Osteoarthritis via Regulating Chondrocyte Autophagy and Cartilage Homeostasis

Osteoarthritis (OA), which is identified by chronic pain, impacts the quality of life. Cartilage degradation and inflammation are the most relevant aspects involved in its development. Signal transducer and activator of transcription 3(STAT3), a member of the STATs protein family, is associated with...

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Detalles Bibliográficos
Autores principales: Pei, Wenbin, Huang, Xiaojian, Ni, Bowei, Zhang, Rui, Niu, Guangyi, You, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505527/
https://www.ncbi.nlm.nih.gov/pubmed/34650433
http://dx.doi.org/10.3389/fphar.2021.730312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505527/
https://www.ncbi.nlm.nih.gov/pubmed/34650433
http://dx.doi.org/10.3389/fphar.2021.730312

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