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Attenuated Salmonella carrying plasmid co-expressing HPV16 L1 and siRNA-E6 for cervical cancer therapy

Human papillomavirus (HPV) infection is the major etiological factor for cervical cancer. HPV prophylactic vaccines based on L1 virus-like particles have been considered as an effective prevention method. However, existing recombination vaccines are too expensive for developing countries. DNA vaccin...

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Detalles Bibliográficos
Autores principales: Chen, Junyu, Zhao, Shuhua, Tan, Wenxi, Wang, Taiwei, Wu, Shan, Wang, Changshuai, Jiang, Yu, Zhou, Tuo, Zhang, Zhuo, Zhao, Lijing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505555/
https://www.ncbi.nlm.nih.gov/pubmed/34635698
http://dx.doi.org/10.1038/s41598-021-99425-3