Homeostatic membrane tension constrains cancer cell dissemination by counteracting BAR protein assembly

Malignancy is associated with changes in cell mechanics that contribute to extensive cell deformation required for metastatic dissemination. We hypothesized that the cell-intrinsic physical factors that maintain epithelial cell mechanics could function as tumor suppressors. Here we show, using optic...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsujita, Kazuya, Satow, Reiko, Asada, Shinobu, Nakamura, Yoshikazu, Arnes, Luis, Sako, Keisuke, Fujita, Yasuyuki, Fukami, Kiyoko, Itoh, Toshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505629/
https://www.ncbi.nlm.nih.gov/pubmed/34635648
http://dx.doi.org/10.1038/s41467-021-26156-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505629/
https://www.ncbi.nlm.nih.gov/pubmed/34635648
http://dx.doi.org/10.1038/s41467-021-26156-4

Ejemplares similares