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Homeostatic membrane tension constrains cancer cell dissemination by counteracting BAR protein assembly
Malignancy is associated with changes in cell mechanics that contribute to extensive cell deformation required for metastatic dissemination. We hypothesized that the cell-intrinsic physical factors that maintain epithelial cell mechanics could function as tumor suppressors. Here we show, using optic...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505629/ https://www.ncbi.nlm.nih.gov/pubmed/34635648 http://dx.doi.org/10.1038/s41467-021-26156-4 |