Nox4 Promotes RANKL-Induced Autophagy and Osteoclastogenesis via Activating ROS/PERK/eIF-2α/ATF4 Pathway

Receptor activator of nuclear factor-κB ligand (RANKL) has been found to induce osteoclastogenesis and bone resorption. However, the underlying molecular mechanisms remain unclear. Via conducting a series of biochemical experiments with in vitro cell lines, this study investigated the role and mecha...

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Detalles Bibliográficos
Autores principales: Sun, Jing, Chen, Wugui, Li, Songtao, Yang, Sizhen, Zhang, Ying, Hu, Xu, Qiu, Hao, Wu, Jigong, Xu, Shangcheng, Chu, Tongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505706/
https://www.ncbi.nlm.nih.gov/pubmed/34650437
http://dx.doi.org/10.3389/fphar.2021.751845

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505706/
https://www.ncbi.nlm.nih.gov/pubmed/34650437
http://dx.doi.org/10.3389/fphar.2021.751845

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