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Nox4 Promotes RANKL-Induced Autophagy and Osteoclastogenesis via Activating ROS/PERK/eIF-2α/ATF4 Pathway

Receptor activator of nuclear factor-κB ligand (RANKL) has been found to induce osteoclastogenesis and bone resorption. However, the underlying molecular mechanisms remain unclear. Via conducting a series of biochemical experiments with in vitro cell lines, this study investigated the role and mecha...

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Detalles Bibliográficos
Autores principales:	Sun, Jing, Chen, Wugui, Li, Songtao, Yang, Sizhen, Zhang, Ying, Hu, Xu, Qiu, Hao, Wu, Jigong, Xu, Shangcheng, Chu, Tongwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505706/ https://www.ncbi.nlm.nih.gov/pubmed/34650437 http://dx.doi.org/10.3389/fphar.2021.751845

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