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Complement Inhibition Targeted to Injury Specific Neoepitopes Attenuates Atherogenesis in Mice

Rationale: Previous studies have indicated an important role for complement in atherosclerosis, a lipid-driven chronic inflammatory disease associated to oxidative stress in the vessel wall. However, it remains unclear how complement is activated in the process of atherogenesis. An accepted general...

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Detalles Bibliográficos
Autores principales: Dai, Shen, Liu, Fengming, Ren, Mi, Qin, Zhongnan, Rout, Namita, Yang, Xiao-Feng, Wang, Hong, Tomlinson, Stephen, Qin, Xuebin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505745/
https://www.ncbi.nlm.nih.gov/pubmed/34651027
http://dx.doi.org/10.3389/fcvm.2021.731315